化学生物学
Chemical Biology
The course
a. Lecture (2 hours per week)
(3:30—5:20 PM, Thursday)
b. Three instructors
1. Shiao (VGH-Taipei) (5)
2. Lin (6)
3. Lee (4)
About the course evaluation
萧明熙 台北荣民总医院 教学研究部
Tel: (02)28712121 Ext. 3363
What is chemical biology
>>To understand the biological functions at the molecular and cellular levels by using the chemical tools (including chemical principles and chemicals as tools)
a. DNA and RNA
b. Proteins
c. Carbohydrates
d. Low-molecular-weight metabolites
Aims of this course
a. To bridge between (organic) chemistry and biology
b. To interpret the chemical principles that govern the biological functions at the molecular and cellular levels
c. To provide chemical basis of the complicated biological systems
d. To link organic chemistry with courses of biochemistry and cell biology
Textbook
The World of the Cell, 5th edition
Benjamin Cummings Publisher (2003)
Becker W. M., L. J. Kleinsmith, and J. Hardin, eds.
>>Other supportive references will be provided.
Date and titles of part 1 (Shiao)
_______________________________________
2/19 The chemistry of the cell (2)
2/26 The macromolecules of the cell (3)
3/4 Bioenergetics (5, 13)
3/11 Membranes and transport across the
membranes (7, 8)
3/18 Enzymes (6)
_______________________________________
Chapter 2: The Chemistry of the Cell
细胞内的化学
>>生命的基本单位是细胞 (cells),生命体是由许多分工复杂的细胞所组成,高等生命体须能执行生长,生殖,新陈代谢,对生长环境具有反应能力等等生命现象.生命科学 (life science) 泛指研究生命体何以能表现生命现象的科学.
>>>生命现象均可视为生命的基本单位 (细胞) 因其所含的生物分子 (biomolecules) 特质,依化学与物理原则运作下所呈现的.了解生物分子的基本化学性质,有助於掌握生命现象的原理和规律.细胞运作的化学原理并无因控管生命现象而有不同.

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