0fOncol Prey andTreat,June2009,VoLI,Nn2
·109·
13I-淀粉样蛋白在卵巢癌组织中的表达及与临床关系研究
于 飞△ 李力
王
琪
张玮
阳志军姚德生
张洁清唐步坚
作者单位:530021南宁广西医科大学肿瘤医院妇瘤科;△广西医科大学研究生学院 【摘要】目的研究B·淀粉样蛋白(Amyloid
beta A4
protein,APP)mRNA在卵巢肿瘤患者组织中的表达,并探讨其临床
意义.方法Trlzol一步法提取卵巢肿瘤患者卵巢组织总RNA,实时荧光定量PCR技术对49例卵巢癌,20例卵巢良性 肿瘤,16例正常卵巢组织进行定量分析.结果APP mBNA在卵巢癌中表达量比在卵巢良性肿瘤和正常卵巢组织中明 显升高(P<0.05);卵巢颗粒细胞瘤患者组织APP的表达显著高于上皮性卵巢癌(P
Expression of significance
YU Fei,LI Li,WANG
beta A4
protein;实时荧光定量PCR;临床分析
【文献标识码】A
【文章编号】1674-5671(2009)02·109-05
and its relationship with clinical
13-amyloid
A4 protein in ovarian
cancer
Qi,et aL(Department
of Gynecological Oneology,Tumor Hospital of Guangxi Medical University,
Nanning Gnangxi 530021,China)
【Abstract】Objective
tumor tissues
Ca8C8
To study the expression of
B-amyloid A4 protein(Amyloid and 16
beta A4
protein,APe)mRNA
in ovarian
and
its clinical
signillcan眈Methods One-step阿础extraction
ease8
method WaB used to extract the total BNA from 49